Comprehensive Osteopathic Medical Licensing Examination (COMLEX-USA) Syllabus

Comprehensive Osteopathic Medical Licensing Examination (COMLEX-USA) covers 8 subjects: Osteopathic Principles, Practice, and Manipulative Treatment (OPP/OMT), Foundational Biomedical Sciences, Internal Medicine and Medical Subspecialties, Surgery, Emergency Medicine, and Musculoskeletal Care, Family Medicine, Primary Care, and Health Promotion, Behavioral Health, Psychiatry, and the Nervous System, Women's Health, Pediatrics, and the Lifecycle and Clinical Skills, Ethics, and Professional Practice. Together they contain 34 chapters and 133 named topics.

The full Comprehensive Osteopathic Medical Licensing Examination (COMLEX-USA) outline breaks down into 34 chapters, 133 topics and 228 sub-topics. Internal Medicine and Medical Subspecialties is the largest single subject with 22 topics across 5 chapters.

Roughly 145 hours for one full pass. That estimate allows about 45 minutes per topic plus 12 minutes per sub-topic, so it is first-pass coverage — revision, past papers and mock tests sit on top of it. At 3 hours a day that is about 7 weeks.

Yes — 444 question-and-answer flashcards across 8 decks, one per subject, written against this syllabus. A sample of every deck is readable on this site for free, and the complete decks are in the Examius app.

Yes. Every page here is free to read, and importing the Comprehensive Osteopathic Medical Licensing Examination (COMLEX-USA) syllabus into the Examius app to tick off topics as you finish them is free too, in United States and everywhere else. No account is needed to start.